Publicaciones del CEP

(Si desea obtener copia de algún artículo, lo puede solicitar a la dirección electrónica que aparece al final de cada título)

Años: 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005

 

2015

  1. García M de L, Borrero R, Lanio ME, Tirado Y, Alvarez N, Puig A, Aguilar A,Canet L, Mata Espinoza D, Barrios Payán J, Sarmiento ME, Hernández-Pando R, Norazmi MN, Acosta A. 2015. Protective effect of a lipid-based preparation from Mycobacterium smegmatis in a murine model of progressive pulmonary tuberculosis. Biomed Res Int. 2014;2014:273129. doi: 10.1155/2014/273129. Epub 2015 Dec 7.PubMed PMID: 25548767; PubMed Central PMCID: PMC4274834.(lcanet@fbio.uh.cu)
  2. López-Abarrategui C., McBeth C., Mandal S.M., Zhenyu J. Sun., Heffron G.,Alba- Menéndez A., Migliolo L., Reyes-Acosta O., García-Villarino M., Nolasco D., Falcão R. , Cherobim M.D. , Dias S.C., Brandt W., Wessjohann L., Starnbach M., Franco O.L. and Otero-González A.J.2015. Cm-p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae). Aceptada en FASEB Journal (Web of Sci; IP: 5.48;SJR: 3.12; H: 212) FASEB Journal, 29(8): 3315-25. (aotero@fbio.uh.cu)
  3. Rossana García-Fernández, Markus Perbandt, Dirk Rehders , Yamile González-González, Patrick Ziegemuller , Nicolas Pigoneau,  Maria Chavez, Ulrich Hahn,  Christian Betzel , Lars Redecke. 2015. Insights into the first 3D-structure of a BPTI Kunitz Type inhibitor -1 in complex with pancreatric elastase  JBC VOL. 290, NO. 22, pp. 14154 –14165. (Rossana@fbio.uh.cu)
  4. Valle, A.; Alvarado-Mesén, J.; Lanio, M. E. ; Álvarez, C.; Barbosa, J.A.R.G. ; Pazos, I.F. 2015. The multigene families of actinoporins (Part I): Isoforms and genetic structure. TOXICON, aceptado Toxicon. Sep 1;103:176-87 (aiselvalle@fbio.uh.cu)
  5. Fidel E Morales, Hilda E Garay, Daniela F Muñoz, Yarelys E Augusto, Anselmo J Otero-González, Osvaldo Reyes Acosta, Daniel G Rivera. 2015. Aminocatalysis-Mediated on-Resin Ugi Reactions: Application in the Solid-Phase Synthesis of N-Substituted and Tetrazolo Lipopeptides and Peptidosteroids. Organic Letters 05/2015; DOI:10.1021/acs.orglett.5b01147. (aotero@fbio.uh.cu)
  6. Viana, Juliane; Souza, Jessica; Freitas, Camila; Paul, Arghya; Alcaraz, Jarib; Lacorte, Cristiano; Migliolo, Ludovico; Andrade, Cesar A. S; Falcao, Rosana; Santos, Nuno; Goncalves, Sonia; Otero-Gonzalez, Anselmo; Khademhosseini, Ali; Dias, Simoni; L. Franco, Octavio. 2015. Antifungal nanofibers made by controlled release of sea animal derived peptide. Nanoscale 03/2015; 7(14). DOI:10.1039/C5NR00767D. (aotero@fbio.uh.cu)
  7. Ros U and Garcia-Saez AJ. More than a pore: the interplay of pore forming proteins and lipid membrane. 2015. Journal of Membrane Biology 06/2015; DOI:10.1007/s00232-015-9820-y
  8. Yamunadevi Subburaj, Uris Ros, Eduard Hermann, Rudi Tong , and Ana J. García-Saez. 2015. Toxicity of an -Pore-forming Toxin Depends on the Assembly Mechanism on the Target Membrane as Revealed  by Single Molecule Imaging (2015) THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 290, NO. 8, pp. 4856–4865,
  9. Hernández González JE, García-Fernández R, Valiente P A. 2015. Polar Desolvation and Position 226 of Pancreatic and Neutrophil Elastases Are Crucial to Their Affinity for the Kunitz-Type Inhibitors ShPI-1 and ShPI-1/K13L. Plos One (valiente@fbio.uh.cu)
  10. Miranda W, Noskov S, and Valiente PA. 2015. Improving the LIE method for binding free energy calculations of protein-ligand complexes. Journal of Chemical Information and Modeling (DOI: 10.1021/acs.jcim.5b00012). (valiente@fbio.uh.cu)
  11. Hernández Alvarez L, Naranjo Feliciano D, Hernández González JE, Soares RO, Barreto Gomes DE, Pascutti PG. 2015. Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches. PLoS Negl Trop Dis. 9(5):e0003759. (DOI: 10.1371/journal.pntd.0003759). (valiente@fbio.uh.cu)
  12. Ros U, Rodríguez-Vera W, Pedrera L, Valiente PA, Cabezas S1, Lanio ME1, García-Sáez AJ2, Alvarez C3.. 2015. "Differences in activity of actinoporins are related with the hydrophobicity of their N-terminus." Biochimie 116: 70-78. (calvarez@fbio.uh.cu)
  13. Reytor ML, Reverter D, Trejo S, de Los Ángeles Chávez M, Avilés FX, Del Rivero MA 2015. Crystal structure of a tri domain BPTI Kunitz inhibitor in complex with human carboxypeptidase A4 revealed a novel and non canonical inhibition mechanism. J Biomol Struct Dyn. May;33 Suppl 1:136-7. doi: 10.1080/07391102.2015.1032840. (maday@fbio.uh.cu)
  14. Ahumada, M., C. Calderon, Alvarez C, Lanio ME, Lissi EA. 2015. "Response of unilamellar DPPC and DPPC:SM vesicles to hypo and hyper osmotic shocks: A comparison." Chem Phys Lipids 188: 54-60. (calvarez@fbio.uh.cu)
  15. Pedrera L, Gomide AB, Sánchez RE, Ros U, Wilke N4, Pazos F1, Lanio ME1, Itri R2, Fanani ML, Alvarez C.  2015. "The Presence of Sterols Favors Sticholysin I-Membrane Association and Pore Formation Regardless of Their Ability to Form Laterally Segregated Domains." Langmuir. Sep 2 (calvarez@fbio.uh.cu)
  16. Mena Valdés Licet, Tamargo Santos Beatriz, Salas Olivet Eva, Plaza Paredes Luis Enrique, Blanco Hernández Yisel, Otero González Anselmo et al . 2015. Determinación de saponinas y otros metabolitos secundarios en extractos acuosos de Sapindus saponaria L. (jaboncillo). Rev Cubana Plant Med  [revista en la Internet]. Mar [citado  2015  Sep  07];  20(1): 106-116. (aotero@fbio.uh.cu)
  17. Isel Pascual, Gabriela García, Laura Sánchez,  Lisset Díaz, Llilian Arzola, Nelson Labrada, Yarini Arrebola, William Ernesto Miranda, María de los Angeles Chávez, Pedro Valiente y Jean-Louis Charli. 2015. La Aminopeptidasa N de mamíferos: características bioquímicas, funciones fisiológicas y su implicación en procesos fisiopatológicos en humanos / Aminopeptidase N from mammals: biochemical caracteristics, physiological functions and implication in physiopathological processes in humans... RCCB 4.1 Pp: 2-16. (isel@fbio.uh.cu)
  18. Carlos López-Abarrategui, Anselmo J. Otero-González, Annia Alba-Menéndez, Edilso Reguera-Ruiz, and Octavio Luiz Franco. 2015. Nanoparticles as a Promise for Host Defense Peptide Therapeutics. In “Biological and Pharmaceutical Applications of Nanomaterials” (Polina Prokopovich Ed). CRC Press, Taylor and Francis Group, London,  Chapter 5, Pags 129-148. ISBN 9781482250169. (aotero@fbio.uh.cu)

 

2014

  1. Cruz-Leal Y, Machado Y, López-Requena A, Canet L, Laborde R, Marcelino Alvares A, Laurindo MF, Santo Tomas JF, Alonso ME, Alvarez C, Arruda R, Popi AF, Mariano M, Pérez R, Lanio ME..2014. Role of B-1 cells in the immune response against an antigen encapsulated into phosphatidylcholine-containing liposomes. Int Immunol  PMID:    24618118 (mlanio@fbio.uh.cu)
  2. Cruz-Leal Y, Lucatelli Laurindo MF, Osugui L, Luzardo MD, López-Requena A, Alonso ME, Alvarez C, Popi AF, Mariano M, Pérez R, Lanio ME. 2014. Liposomes of phosphatidylcholine and cholesterol induce an M2-like macrophage phenotype reprogrammable to M1 pattern with the involvement of B-1 cells. Immunobiology. Feb 3. pii: S0171-2985(14)00023-0. doi: 10.1016/j.imbio.2014.01.006. (mlanio@fbio.uh.cu)  
  3. Martinez Duniesky a,⇑, Cutino-Avila Bessy b, Perez Enrique Rosendo a, Menendez Carmen, Hernandez Lazaro c, del Monte-Martinez Alberto. 2014. A thermostable exo-b-fructosidase immobilised through rational design Food Chemistry 145 (2014) 826–831. (adelmonte@fbio.uh.cu)
  4. Alberto del Monte-Martinez, Jorge Gonzalez-Bacerio a, Lazara Romero a, Carlos Aragon, Diana Martinez, Maria de los A. Chavez a, Carlos Alvarez a, Maria E. Lanio Jose M. Guisan, Joaquin Diaz. 2014. Improved purification and enzymatic properties of a mixture of Sticholysin I and II: Isotoxins with hemolytic and phospholipase A2 activities from the sea anemone Stichodactyla helianthus Protein Expression and Purification 95 57–66 (adelmonte@fbio.uh.cu)
  5. Javier Alvarado, Yeney Álvarez, Lohans Pedrera, Uris Ros, María E Lanio, Aisel Valle, Carlos Álvarez2 . 2014. Isolation and partial purification of a hemolytic sphingomyelin-inhibitable fraction from the sea anemone Anthopleura nigrescens, Biotecnologia aplicada. 31:53-56 (calvarez@fbio.uh.cu)
  6. Pedrera L, Fanani ML, Ros U, Lanio ME, Maggio B, Alvarez C. 2014. Sticholysin I-membrane interaction: An interplay between the presence of sphingomyelin and membrane fluidity. Biochim Biophys Acta. Mar 26;1838(7):1752-1759(calvarez@fbio.uh.cu)
  7. B. Cutiño-Avila, D. Gil Pradas, C. Aragón Abreu, Y. Fernández Marrero, M. Hernández de la Torre, E. Salas Sarduy, M.A. Chávez Planes, J.M. Guisán Seijas, J. Díaz Brito, A. del Monte-Martínez. 2014. Computer-aided design of bromelain and papain covalent immobilization. Rev. Colomb. Biotecnol. Vol. XVI No. 1, 19-28. (adelmonte@fbio.uh.cu)
  8. Luis Leon Maturana, Eduardo Lissi, Gloria Celedon, Gustavo Gonzalez, Fabiola Pazos, Carlos Alvarez, Maria E. Lanio. 2014. Inactivation of the pore-forming toxin sticholysin I by peroxynitrite. Protection by Cys groups incorporated in the toxin"  Protein J. Sep 14. [Epub ahead of print] (mlanio@fbio.uh.cu)
  9. Jorge González-Bacerio, Joel Osuna, Amaia Ponce, Rafael Fando, Katherine Figarella, Yanira Méndez, Jean-Louis Charli, María Á. 2014. High-level expression in Escherichia coli, purification and kinetic characterization of Plasmodium falciparum M1-aminopeptidase. Chávez. Protein Expression and Purification. Volumen 104, , diciembre, pp. 103-114. (jogoba@fbio.uh.cu)
  10. Yanira Méndez, Karell Pérez-Labrada, Jorge González-Bacerio, Gilberto Valdés, María Á de Los Chávez, Joel Osuna, Jean-Louis Charli, Isel Pascual, Daniel G Rivera.2014.  Combinatorial Multicomponent Access to Natural-Products-Inspired Peptidomimetics: Discovery of Selective Inhibitors of Microbial Metallo-aminopeptidases ChemMedChem 07/2014; ·doi: 10.1002/cmdc.201402140 (jogoba@fbio.uh.cu)  
  11. Yarini M Arrebola, Hansel Gómez, Pedro A Valiente, Maria de los A Chávez, Isel Pascual* .2014. Dipeptidyl peptidase IV and its implication in cancer . Biotecnología Aplicada 31 (2): 102-110 (Isel@fbio.uh.cu)
  12. Yarini M Arrebola, Hansel Gómez, Pedro A Valiente, Maria de los A Chávez, Isel Pascual*. 2014. Dipeptidil peptidasa IV y su implicación en cancer . Biotecnología Aplicada 31 (2): 93-101. (Isel@fbio.uh.cu)
  13. Alba A1, Hernández HM, Marcet R, Gil AL, Vázquez AA, Figueredo M, Sánchez J, Garay HE, 2014. Exploring the antigenic features of Fasciola hepatica rediae (Trematoda: Digenea) through the evaluation of different antigenic candidates for further monoclonal antibody generation. Sarracent J. Parasitol Res. Jun 13.
  14. Jorge González-Bacerio, Rafael Fando, Alberto del Monte, Jean-Louis Charli, María Á. Chávez. 2014. Plasmodium falciparum M1-aminopeptidase: a promising target for the development of antimalarials (Review). Current Drug Targets. EEUU. 15, 1144-1165 (jogoba@fbio.uh.cu)
  15. Carmen Menéndez, Duniesky Martínez, Luis E. Trujillo, Ricardo Ramírez1, Alina Sobrino, Bessy V. Cutiño-Ávila, Liliana Basabe, Alberto del Monte-Martínez,  Enrique R. Pérez, Lázaro Hernández. 2014. Development of soluble and immobilized biocatalysts based on a recombinant thermostable b-fructosidase enabling complete sucrose inversion at pasteurization temperatures. Biotecnol. Apl., 31(3), 249-253. ISSN 1027-2852.
  16. Leon, L., E. A. Lissi,  Celedón G, Gonzalez G, Pazos F, Alvarez C, Lanio ME. 2014. "Inactivation of the pore-forming toxin Sticholysin I by peroxynitrite: protection by cys groups incorporated in the toxin." Protein J 33(5): 493-501. (mlanio@fbio.uh.cu)
  17. Maday Alonso-del-Rivero Antigua, María de los Ángeles Chávez Planes, Mey Ling Reytor Gonzalez, Gilberto Valdés, Julieta Delfín Garcia, Joaquin Diaz Brito, Rossana Garcia Fernández, Dagmara Díaz Diaz, Yamile González González. 2014. Una nueva metalocarboxipeptidasa y un nuevo inhibidor bifuncional de serino/metalo proteasas aislados del anélido marino Sabellastarte magnifica: Estructura y función. Revista Anales de la Academia de Ciencias de Cuba. 4 (2): 1-7 (maday@fbio.uh.cu)
  18. Rossana García Fdez, María A. Chávez Planes,  Yamile Glez Glez, Tirso Pons Hdez, Dayrom Gil Pradas, Caridad Mireya Romero Tió. 2014. Obtención y caracterización cinética y estructural de dos variantes recombinantes de ShPI-1, inhibidor de proteasas de la anémona Stichodactyla helianthus, y de sus complejos con tripsina, quimotripsina y elastasa. Revista Anales de la Academia de Ciencias de Cuba. 4 (2): 1-7 (Rossana@fbio.uh.cu)
  19. Pedro Alberto Valiente Flores, Tirso Pons Hernández, Alejandro Gil Ley, Yasel Guerra Borrego, Isel Pascual Alonso, Williams Ernesto Miranda Delgado y  Yusvel Sierra Gómez. 2014. Análisis in silico de la naturaleza de las interacciones que determinan la especificidad y la selectividad de la plasmepsina II del Plasmodium falciparum por sus sustratos e inhibidores: implicaciones para el diseño de inhibidores más selectivos Revista Anales de la Academia de Ciencias de Cuba. 4 (2): 1-7 (valiente@fbio.uh.cu)
  20. García M de L, Borrero R, Lanio ME, Tirado Y, Alvarez N, Puig A, Aguilar A,Canet L, Mata Espinoza D, Barrios Payán J, Sarmiento ME, Hernández-Pando R, Norazmi MN, Acosta A. Protective effect of a lipid-based preparation from Mycobacterium smegmatis in a murine model of progressive pulmonary tuberculosis. Biomed Res Int. 2014;2014:273129. doi: 10.1155/2014/273129. Epub 2014 Dec 7.PubMed PMID: 25548767; PubMed Central PMCID: PMC4274834 (mlanio@fbio.uh.cu)
  21. Jorge Oscar González Bacerio, UrisLianne Ros Quincoces, Alina Forrellat Barrios. 2014. Enseñanza de la Bioquímica para las carreras de Biología y Microbiología de la Facultad de Biología, Universidad de La Habana, en el Plan de Estudio D. RCCB 3(1): 50 – 58. (jogoba@fbio.uh.cu)
  22. Yarini Manuel Arrebola Sánchez, Lisset Díaz Guevara, Gabriela García Rodríguez, Isel Pascual Alonso.  2014. Dipeptidil peptidasa IV: inhibidores y sus potenciales aplicaciones biomédicas / Dipeptidil peptidase IV: inhibitors and potentials biomedical applications RCCB 3(2) : 14-26. (Isel@fbio.uh.cu)
  23. Yadira de la Patria Hervis Valdés, Aisel Valle Garay, Liem Canet Santos, Carlos Manuel Álvarez Valcárcel, María Eliana Lanio Ruiz, Isabel Fabiola Pazos Santos. 2014. Importancia funcional de la Pro80 para la interacción con membranas y la formación de poros por la sticholysina I, actinoporina de Stichodactyla helianthus (Anthozoa: Stichodactylidae)      RCCB 3(2) : 27-40 (fpazos@fbio.uh.cu)
  24. Del Monte Martinez A., Cutiño Avila B., Gonzalez Baceiro J., Chaves MA., Diaz J. . 2014. Diseño Racional en la inmovilización de proteínas: aplicaciones en afinidad y en bioconversion de proteínas Revista Anales de la Academia de Ciencias de Cuba Vol 4 No1 pp  G2 scielo (adelmonte@fbio.uh.cu)
  25. María Eliana Lanio, Fabiola Pazos, Rosangela Itri, Shirley Schreier, Luis E. Fernández, Carlos Álvarez Proteínas Formadoras de Poros de Stichodactyla helianthus y sus Aplicaciones en la Biomedicina. pp. 37-57. En “Temas seleccionados de toxinas con implicaciones biomédicas y métodos para su estudio” (calvarez@fbio.uh.cu)
  26.  Rodrigo Montecinos, Eduardo Lissi, Carlos Alvarez, María Eliana Lanio, Fabiola Pazos Interactions of Sticholysin I with DPPC/SM bilayers. A Molecular Dynamics study.. PP.96-113. En “Temas seleccionados de toxinas con implicaciones biomédicas y métodos para su estudio”. (fpazos@fbio.uh.cu)

 

2013

  1. Hansel Gómez, Mae Chappé , Pedro Valiente, Tirso Pons, María de los Angeles Chávez , Jean-Louis Charli and IselPascual (2013) Effect of zinc and calcium ions on the rat kidney membrane-bound form of dipeptidyl peptidase IV. Journal of Biosciences.38.3: 1-9 (isel[at]fbio.uh.cu)
  2. Ros U., Edwards M.A, Epand R.F., Lanio M.E., Schreier S., Yip C.M., Alvarez C., Epand R.M. The sticholysinfamily of pore-forming toxins induce the mixing of lipids in membrane domains. (2013). Biochimica et Biophysica Acta 1828. 2757.2762.(uris[at]fbio.uh.cu)
  3. Ros U., Souto A.L., de Oliveira F.L, Crusca E.J., Pazos, F., Cilli E.M., Lanio, M.E., Schreier, S., Alvarez, C. Functional and topological studies with Trp-containing analogs of the peptide StII1-30 derived from the N-terminus of the pore forming toxin sticholysin II: contribution to understand its orientation in membrane. (2013). Biopolymers (Peptide Science) 100 (4): 337-346 (uris[at]fbio.uh.cu)
  4. López-Abarrategui, C; Figueroa-Espí, V; Reyes-Acosta, O; Reguera, E; Otero-González, AJ (2013) Magnetic nanoparticles: New players in antimicrobial peptide therapeutics. Current Protein and Peptide Science, vol 14(7): Aug 2. [Epub ahead of print] (clopez[at]fbio.uh.cu)
  5. López-Abarrategui C. and Otero-González AJ. (2013) Subcellular proteomics for understanding Host Defense Peptides mechanism of action.Review article. Organelles Proteomics, 1: 7-15. DOI: 10.2478/orpr-2013-0003 . ORPR . 2013 . 7.15 No (Número inicial) (clopez[at]fbio.uh.cu)
  6. Loiane Lima, Ludovico Migliolo, Clovis Castro, Debora Pires, Carlos Lopez-Abarrategui, Eveline Gonçalves, Ilka Vasconcelos, Jose Oliveira, Anselmo Otero-Gonzalez, SimoniDias and Octavio L. Franco (2013) Identification of a Novel AntimicrobialPeptidefromBrazilianCoast Coral Phyllogorgiadilatata. Protein & Peptide Letters, 20(10): 1153.158. (aoterog[at]infomed.sld.cu)
  7. B. Cutiño-Avila, E. Cunill-Semanat, D.F. Gil, M.A. Chávez, J. Díaz, A. del Monte-Martínez.Synthesis of Tetanus Toxoid-Sepharose CL 4B derivatives by Rational Design. In: V Latin American Congress on Biomedical Engineering CLAIB 2011, IFMBE Proceedings Volume 33, José Folgueras Méndez, Tania Y. Aznielle Rodríguez, Carlos F. CalderónMarín, Susana Beatriz Llanusa Ruiz, Jorge Castro Medina, Haddid Vega Vázquez, MaylenCarballoBarreda, Rafael Rodríguez Rojas (Eds.), (2013) pp 160-163. Print ISBN 978-3-642-21197-3, Online ISBN 978-3-642-21198-0, Series ISSN 1680-0737, Springer Science+Business Media Berlin Heidelberg, DOI 10.1007/978-3-642-21198-0_41.(adelmonte[at]fbio.uh.cu)
  8. A.del Monte-Martínez, B. Cutiño-Avila, D. Gómez, I. Pereda, J. Díaz, J. Rojas. Computational mathematic model for the immobilization of cells and proteins on charged solid surfaces by electrostatic interactions. In: V Latin American Congress on Biomedical Engineering CLAIB 2011, IFMBE Proceedings Volume 33, José Folgueras Méndez, Tania Y. Aznielle Rodríguez, Carlos F. CalderónMarín, Susana Beatriz Llanusa Ruiz, Jorge Castro Medina, Haddid Vega Vázquez, MaylenCarballoBarreda, Rafael Rodríguez Rojas (Eds.), (2013) pp 73-76. Print ISBN 978-3-642-21197-3, Online ISBN 978-3-642-21198-0, Series ISSN 1680-0737, Springer Science+Business Media Berlin Heidelberg, DOI 10.1007/978-3-642-21198-0_19.(adelmonte[at]fbio.uh.cu)
  9. Borrero R., García M.A., Canet L., Zayas C., Reyes F., Prieto J.L., Infante J. F., Lanio M.E., Kadir R., López Y., Sarmiento M. E., Norazmi M. N., Acosta A. Evaluation of the humoral immune response and cross reactivity against Mycobacterium tuberculosis of mice immunized with liposomes containing glycolipids of Mycobacterium smegmatisBMC Immunology 2013, 14(Suppl 1), S13, 1-4. (mlanio[at]fbio.uh.cu)
  10. Evaluation of specific humoral immune response and cross reactivity against Mycobacterium tuberculosis antigens induced in mice immunized with liposomes composed of total lipids extracted from Mycobacterium smegmatis.García M.A., Borrero R., Marrón R., Lanio M.E., Canet L., Otero O., Kadir R., Suraiya S., Zayas C., López Y., Norazmi M. N., Sarmiento M. E., Acosta A. BMC Immunology 2013, 14(Suppl 1), S11, 1-5. (mlanio[at]fbio.uh.cu)
  11. Perez-Riverol Y, Hermjakob H, Kohlbacher O, Martens L, Creasy D, Cox J, Leprevost F, Shan BP, Pérez-Nueno VI, Blazejczyk M, Punta M, Vierlinger K, Valiente PA, Leon K, Chinea G, Guirola O, Bringas R, Cabrera G, Guillen G, Padron G, Gonzalez LJ, Besada V. (2013) ComputationalProteomicsPitfalls and Challenges: HavanaBioinfo 2012 WorkshopReport. J Proteomics.2013 Jan 29.doi:pii: S1874-3919(13)00049-3. (valiente[at]fbio.uh.cu)
  12. Alonso-del-Rivero M., ReytoR ML., Trejo SA., Chávez MA., Avilés FX., and Reverter D. (2013) A novel and non-canonical mechanism of carboxypeptidase inhibition revealed by the crystal structure of the tri-KunitzSmCI in complex with human CPA4. Structure21, 1118.1126 (maday[at]fbio.uh.cu)
  13. Emir Salas Sarduy; Aymara Cabrera-Muñoz; Ana Cauerhff; Yamile González-González; Sebastián A Trejo; Agustina Chidichimo; Maria A Chávez Planes; Juan J Cazzulo (2013). Antiparasitic effect of a fraction enriched in tight-binding protease inhibitors isolated from the Caribbean coral Plexaurahomomalla. Experimental ParasitologySep 30. pii: S0014-4894(13)00258-0. doi: 10.1016 (mchavez[at]infomed.sld.cu)
  14. Ros U., Pedrera L., Martínez D., Tejuca M., Pazos F., Lanio M.E., Alvarez C. Synthetic peptides that reproduce the N-terminus of sticholysins as models for the study of their structure-function relationship. (2013). Biotecnología Aplicada 30(4): 1-5(ros[at]fbio.uh.cu)
  15. Alberto del Monte-Martínez, Bessy V. Cutiño-Avila, Jorge O. González-Bacerio, Darío González-Abradelo, Viviana Figueroa Espí y Roberto Cao-Vázquez. Aplicación de enzimas en biocatálisis. Perspectivas de la utilización de nanoarreglos como biocatalizadores. REVISTA CUBANA DE CIENCIAS BIOLÓGICAS. (2013) Vol. 2 (2): 7-23. Rnps: 2362 . ISSN: 2307-695X. (adelmonte[at]fbio.uh.cu)
  16. Pentón-Madrigal, A., Estevez-Rams, E,. Reguera, E., Rodríguez-Hernández, J. Concepción-Rosabal, B., García-Basabe, Y., García-Fernández, R., Talavera, A., Moreno, E. (2013) A decade of Cuban presence in Synchrotronlighsourcefacilities. Rev. Cub. Fis. 30, 36-41. (Rossana[at]fbio.uh.cu)
  17. Yamilé González, Dayrom Gil, Maday Alonso del Rivero, Isel Pascual, Rossana García, Julieta Delfín, Joaquín Díaz, Mariana S. Araujo, Aparecida S. Tanaka, Tirso Pons y María A. Chávez (2013) Inhibidores de serino proteasas de naturaleza proteica aislados de invertebrados marinos. Revista Cubana de Ciencias Biológicas. 2(1):5-13 (maday[at]fbio.uh.cu)
  18. Maday Alonso del Rivero, Yamilé González, Isel Pascual, Rossana García, Julieta Delfín, Joaquín Díaz y María A. Chávez (2013) Multifunctionalproteasesinhibitors of proteicnature. Revista Cubana de Ciencias Biológicas.2(1):14-21 (maday[at]fbio.uh.cu)

2012

  1. Oliveira-Santos J, Nunes VA, Cruz-Silva I, Praxedes-Garcia P, Gozzo AJ, Rydlewski M, González-González Y, Nader HB, Araujo MS (2011) GlycosaminoglycansModifyelastaseAction In Vitro and EnhanceElastase-InducedCellDeath in CulturedFibroblastsCellBiologyVol 2012G1 web of Science (ygonzalez64[at]yahoo.com)
  2. Lovato DV. , Amino R, González Y, Miranda A, Schenkman S, Tanaka AS (2011) Infestin 1R, an intestinal subtilisin inhibitor from Triatoma infestans able to impair mammalian cell invasion by Trypanosoma cruziExp. Parasitology 129: 362.367(IF: 2.212) Scopus. G1 (ygonzalez64[at]yahoo.com)
  3. López-Abarrategui, C., Alba-Menéndez, A., Silva, ON, Reyes- Acosta, O., Vasconcelos, IM., Abreu de Oliveira, JT., Migliolo, L., Costa, MP, Costa, CR., Silva, MRR, Garay, HE, Dias, SC, Franco, OL and Otero-González, AJ. (2012) Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritismuricatus. Biochimie, 94: 968-974 (IP: 3.78, G1), MedLine, Web of Science. (aoterog[at]infomed.sld.cu)
  4. Annia Alba, Carlos López-Abarrategui, Anselmo J. Otero-González (2012) Host DefensePeptides: A TherapeuticAlternative As AntiiInfectiveDrugs And ImmunomodulatoryTherapeutics. Biopolymers: Peptide Sciences 98(4): 251-267 (IP: 2.55, G1), MedLine, Web of Science. (aoterog[at]infomed.sld.cu)
  5. Carlos López-Abarrategui, Annia Alba-Menéndez, Loiane A. Lima1, Simone Maria-Neto, Ilka M. Vasconcelos, Jose T. A. Oliveira, Simoni C. Dias, Anselmo J. Otero-Gonzalez and Octavio L. Franco (2012) Screening of antimicrobials from Caribbean sea animals and isolation of bactericidal proteins from the littoral mollusk Cenchritismuricatus. Current Microbiology64: 501-505 (IP: 1.81, G1), MedLine, Web of Science. (aoterog[at]infomed.sld.cu)
  6. Silva, ON., Mulder, KCL., Barbosa, AEAD, Otero-Gonzalez, AJ, Lopez- Abarrategui, C., Rezende, TMB. Dias, SC and Franco, OL (2011) Exploring the pharmacological potential of promiscuous host defense peptides: from natural screenings to biotechnological applications. Frontiers in Microbiology, 2: 1-14 (IP: 1.08, G1), MedLine, Web of Science. (aoterog[at]infomed.sld.cu)
  7. Simone Maria-Neto, Elizabeth Candido, Diana Ribas, Daniel Souza, Ezequiel Silva, Lidia Pepe, Anselmo Otero-González, Beatriz Magalhães, Simoni Dias, and Octávio Franco. Deciphering the magainin-resistance process of Escherichia coli strains in light the cytosolic proteome (2012) Antimicrobial Agents and Chemotherapy. 56(4): 5558-11. (IP: 4.84, G1), MedLine, Web of Science. (aoterog[at]infomed.sld.cu)
  8. Alonso-del-Rivero M, Trejo SA, Reytor ML, Rodriguez-de-la-Vega M, Delfin J, Diaz J, González-González Y, Canals F, Chavez MA, Aviles FX. (2012) Tri-domain bifunctional inhibitor of metallocarboxypeptidases A and serine proteases isolated from marine annelid Sabellastartemagnifica.J Biol Chem. 2012 May 4;287(19):15427-38. Epub 2012 Mar 12(IP: 4.773, G1) MedLine, Web of Science. (maday[at]fbio.uh.cu)
  9. Sarduy ES, Muñoz AC, Trejo SA, Chávez Planes MA. (2012) High-level expression of Falcipain- 2 inEscherichia coli by codon optimization and auto-induction. ProteinExpression and Purification; 83(1):59-69 (IP: 1.587, G1) web of Science (mchavez@infomed.sld.cu) (mchavez[at]infomed.sld.cu)
  10. Giovanni Covaleda, Maday Alonso del Rivero, María A. Chávez, Francesc X. Avilés, and David ReverterCrystal Structure of Novel Metallocarboxypeptidase Inhibitor from Marine Mollusk Neritaversicolor in Complex with Human Carboxypeptidase A4 J. Biol. Chem. 2012 287:9250-9258.First Published on January 31, 2012, doi:10.1074/jbc.M111.330100(IP: 4.773, G1) MedLine, Web of Science. (mchavez[at]infomed.sld.cu)
  11. Sarduy ES,Chávez Planes MA. Efficient expression systems for cysteine proteases of malaria parasites: too good to be true? Bioengineered. 2012 Sep 27;4(2). [Epubahead of print] (mchavez[at]infomed.sld.cu)
  12. Ros U., Pedrera L., Diaz D., de Karam J.C., Sundbrack T.P, Valiente, P.A., Martínez, D., Cilli, E.M., Pazos, F., Itri, R., Lanio, M.E., Schreier, S., Alvarez, C. (2011). The membranotropic activity of N-terminal peptides from the pore-forming proteins sticholysin I and II is modulated by hydrophobic and electrostatic interactions as well as lipid composition. J. Biosci. 36 (5): 781-791. (FI:1.9)G1 web of Science (uris[at]fbio.uh.cu)
  13. A. del Monte-Martínez and B.V. Cutiño-Avila. Rational design of immobilized lipases and phospholipases, J. Meth. Mol. Biol. 861(2012) 343.82. Impact Factor: 13.9 G1, Web of Science (adelmonte[at]fbio.uh.cu)
  14. García-Fernández R, Pons T, Perbandt M, Valiente P.A, Talavera A, González Y., Rehders D, Chávez M. A, Betzel Ch, Redecke, L. Structuralinsightsintoserineproteaseinhibitionby a marine invertebrateKunitz-typeinhibitor. J. Struct. Biol. (2012) En prensa (http://dx.doi.org/10.1016/j.jsb.2012.08.009). IF 3.406, Scopus. G1 (rossana[at]fbio.uh.cu)
  15. Bernardo L., Pavón A., Hermida L., Gil L., Valdés I., Cabezas S., Linares R., Alvarez M., Silva R., Guillén G., Nagy E., Schlick P., Guzmán MG. The two component adjuvant IC31(®) potentiates the protective immunity induced by a dengue 2 recombinant fusion protein in mice. Vaccine. 2011; 29: 4256-63. GRUPO 1. WEB OF SCIENCE Web of Science, ELSEVIER, ISSN 0264-410X. IF: 3.766G1 (scabezas[at]fbio.uh.cu)
  16. Guerra Y, Valiente PA, Berry C, and Pons T (2012) Predicting functional residues of the Solanumlycopersicum aspartic protease inhibitor (SLAPI) by combining sequence and structural analysis with molecular docking. Journal of Molecular ModelingVol 18 (6): 2673-2687. Web of Science(FI= 2.184)G1 (valiente[at]fbio.uh.cu)
  17. G Ramos Echazábal, G Chinea, R García-Fernández, T Pons (2012) In silico studies of potential phosphoresidues in the human nucleophosmin/B23: its kinases and related biological processes Journal of Cellular Biochemistry 113 (7), 2364-2374 FI: 2.868 G1. Web of Science (rossana[at]fbio.uh.cu)
  18. García-Fernández R, Pons T, Meyer A., Perbandt M, González Y., Gil D, Chávez M. A, BetzelCh, Redecke, L. Crystal structure of the recombinant BPTI-Kunitz type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus. ActaCryst. F. (2012) Aceptada. IF 0.51, indexada enScopus. DOI:10.1107/S1744309112039085 (rossana[at]fbio.uh.cu)
  19. Alberto del Monte-Martínez, Jorge González-Bacerio, Carlos Aragón-Abreu, JoséMiguel Palomo-Carmona, José Manuel Guisán-Seijas and Joaquín Díaz-Brito. Selective and oriented immobilization of (phospho)lipases from the Caribbean Sea anemone Stichodactylahelianthus(Ellis, 1768) by interfacial adsorption.Revista CENIC Ciencias Biológicas, Vol. 43 (2012), No. 1, p. 3-8.LATINDEX, Chemical Abstract, ILA, EBSCOG2 (adelmonte[at]fbio.uh.cu)
  20. Jorge Oscar González-Bacerio, Gilberto Valdés García, Amaia Ponce de la Cal, Anett Rubio Torres, Sandra Madariaga Zarza, María de los Ángeles Chávez Planes, Isel Pascual Alonso La investigación científica en el campo de la malaria, importancia socioeconómica y ética. Panorama Cuba y Salud. Vol. 7., No. 3, año 2012, septiembre-diciembre, pp: 28-36, Cuba. (jogoba[at]fbio.uh.cu)

    21. Estructuras anotadas en la base de datos "Protein Data Bank" (2 estructuras anotadas)

  21. Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase' (2012). Rossana García-Fernández, Markus Perbandt, Dirk Rehders, Yamile González, María de los Ángeles Chávez, Patrick Ziegemüller, Nicolas Piganeau, Ulrich Hahn, Christian Betzel, Lars Redecke. PDB ID: 3UOU. (rossana[at]fbio.uh.cu)
  22. Structure of the carboxypeptidase inhibitor from the snail Neritaversicolor in complex with human CPA4 G. Covaleda, M Alonsodel Rivero, MA, Chavez, FX Avilés, D. Reverter (2011) PDB code: 4a94 (maday[at]fbio.uh.cu)

2011

  1. Ley AG, Valiente P A, Pascutti PG, and Pons T (2011) Computational Perspectives into Plasmepsins Structure-Function Relationship: Implications to Inhibitor Design. Journal of Tropical Medicine Vol 2011: 657483 (FI=no reportado en 2010 en el sitio del ISI) PUBMED ID: 21760810. (alegil[at]fbio.uh.cu)
  2. V. Figueroa-Espí, A. Alvarez-Paneque, M. Torrens, A.J. Otero-González, E. Reguera (2011) Conjugation of manganese ferrite nanoparticles to an anti Sticholysin monoclonal antibody and conjugate applications. Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol 387(1-3): 118-124. (aoterog[at]infomed.sld.cu)
  3. Torres-Salas P, del Monte-Martínez A, Cutiño-Avila B, Rodríguez-Colinas B, Alcalde M, Ballesteros AO, Plou FJ. (2011) Immobilized Biocatalysts: Novel Approaches and Tools for Binding Enzymes to Supports. Advanced Materials XX: 1-8. DOI: 10.1002/adma.201101821. (adelmonte[at]fbio.uh.cu)
  4. Isel Pascual, Hansel Gómez, Tirso Pons, Mae Chappé, Miguel Angel Vargas, Gilberto Valdés, Alí Lopéz, Angélika Saroyán, Jean-Louis Charli, María de los Angeles Chávez. (2011) Effect of divalent cations on the porcine kidney cortex membrane-bound form of dipeptidyl peptidase IV. International Journal of Biochemistry and Cell Biology. 43, 363.371 (isel[at]fbio.uh.cu)
  5. Gil, D., Garcia-Fernandez, R., Alonso-del-Rivero, M., Lamazares, E., Perez, M., Varas, L., Diaz, J., Chavez, M. A., González-González, Y., Mansur, M. (2011). Recombinant expression of ShPI-1A, a non-specific BPTI-Kunitz-type inhibitor, and its protection effect on proteolytic degradation of recombinant human miniproinsulin expressed in Pichia pastoris. FEMS Yeast Res. Vol 11:7 575-586. (yamile[at]fbio.uh.cu)
  6. Pentón, David; Pérez-Barzaga, Victor; Díaz, Iscel; Reytor, Mey; Campos, Javier; Fando, Rafael; Calvo, Loany; Cilli, Eduardo; Morera, Vivian; Castellanos-Serra, Lila; Pazos, Fabiola; Lanio, María; Álvarez, Carlos; Pons, Tirso; Tejuca, Mayra (2011). Validation of a mutant of the pore-forming toxin sticholysin-I for the construction of proteinase-activated immunotoxins. Protein Engineering, Design, and Selection XXX :1-9, doi:10.1093/protein/gzr002). (tejuca[at]rect.uh.cu)
  7. Garay H, Menéndez T, Cruz-Leal Y, Coizeau E, Noda J, Morera V, Guillén G, Albericio F, Reyes O. (2011) Study of various presentation forms for a peptide mimetic of Neisseria meningitidis serogroup B capsular polysaccharide. Bioconjug Chem. Jan 19; 22(1):33-41. PMID:21141955] (yoelys[at]fbio.uh.cu)
  8. Valle A, López-Castilla A, Pedrera L, Martínez D, Tejuca M, Campos J, Fando R, Lissi E, Alvarez C, Lanio ME, Pazos F, Schreier S. (2011) Cys mutants in functional regions of Sticholysin I clarify the participation of these residues in pore formation. Toxicon. Jul;58(1):8-17. Epub 2011 Apr 13. PubMed PMID: 21510967. (aiselvalle[at]fbio.uh.cu)
  9. Celedón G, González G, Lissi E, Cerda T, Bascuñant D, Lepeley M, Pazos F, Lanio ME, Alvarez C. (2011). Effect of pre-exposure of human erythrocytes to oxidants on the haemolytic activity of Sticholysin II. A comparison between peroxynitrite and hypochlorous acid. Free Radic Res. 45(4):400-8 (calvarez[at]fbio.uh.cu)
  10. del Monte-Martínez A, Cutiño-Avila B, Gómez D, Pereda I, Díaz J, Rojas J. (2011) Computational mathematic model for the immobilization of cells and proteins on charged solid surfaces by electrostatic interactions. In: IFMBE Proceedings Vol 33. 1st Edition, 800 p. Folgueras J, Aznielle TY, Calderón CF, Llanusa SB, Castro J, Vega H, Carballo M, Rodríguez R (Eds.). Softcover, ISBN 978-3-642-21197-3. Springer Science+Business Media. (adelmonte[at]fbio.uh.cu)
  11. Cutiño-Avila B, Cunill-Semanat E, Gil DF, Chávez MA, Díaz J, del Monte-Martínez A. (2011) Synthesis of Tetanus Toxoid-Sepharose CL 4B derivatives by Rational Design. In: IFMBE Proceedings 33. 1st Edition, 800 p. Folgueras J, Aznielle TY, Calderón CF, Llanusa SB, Castro J, Vega H, Carballo M, Rodríguez R (Eds.)., Softcover, ISBN 978-3-642-21197-3. Springer Science+Business Media (adelmonte[at]fbio.uh.cu).
  12. López, A.; Valle, A.; Pedrera, L.; Martínez, D.; Fando, R.; Schreier, S.; Álvarez, C.; Lanio, M.E. y Pazos, F. (2011) The Sticholysin I mutants St I E2C and St I R52C show similar binding to liposomal vesicles but differ in their permeabilizing activity. Biotecnología Aplicada. 28 (1) 2011. (fpazos[at]fbio.uh.cu)
  13. Alba-Menéndez,A., López-Abarrategui, C., Vázquez-Perera,AJ., Otero- González, AJ (2011) Optimización de la solución de extracción de moléculas antibacterianas de Cenchritis muricatus (Gastropoda: Littorinidae). Rev Cub Med Trop 63(2):171-6 (aoterog[at]infomed.sld.cu)
  14. Gonzalez-Gonzalez Y., Gil D., Alonso-del-Rivero M., Besada V., Gil J., Araujo MS., Tanaka., AS., Pons T., Chavez MA. (2010) Novel protease inhibitors active against human neutrophil elastase and plasma kallikrein with therapeutic potentialities: Structure-function relationships. Biotecnología Aplicada 27 (4): 310-313. (yamile[at]fbio.uh.cu)
  15. Mey Ling Reytor, Yamile González, Isel Pascual, Aida Hernández, María Á Chávez, Maday Alonso del Rivero (2011) Screening of protease inhibitory activity in extracts of five Ascidian species from Cuban coasts. Biotecnología Aplicada 28 (2):77-82 (maday[at]fbio.uh.cu)
  16. Carol Carvajal, Margarita Márquez, Aurora T. Pérez, María de los A. Chávez, Martha Hernández. (2010) Caracterización cinética de un preparado semipurificado de bromelina para su uso como antitumoral.. Revista Cubana de Plantas Medicinales, Vol. 15, No. 2, 2010. (mchavez[at]infomed.sld.cu)
  17. María A. Chávez Planes, Joaquín Díaz Brito, María E. Lanio Ruiz y Carlos M. Álvarez Valcárcel (2011). El Centro de Estudio de Proteínas de la Universidad de La Habana: contribución científica y compromiso social. Revista Universidad de La Habana, No 270(mchavez[at]infomed.sld.cu)
  18. Álvarez C, Alonso-del-Rivero M, Hernández A, Díaz J, Lanio ME, Chávez MA. (2010). Biomoléculas de interés biomédico y biotecnológico a partir de organismos marinos: la perspectiva del Centro de Estudio de Proteínas de La Universidad de La Habana. En: La biodiversidad en ecosistemas marinos y costeros del litoral de Iberoamérica y el cambio climático: Memorias del Primer Taller de la Red CYTED BIODIVMAR. pp: 221-233.
    19. Estructuras anotadas en la base de datos "Protein Data Bank"
  19. PDB ID: 3T62 (2011) R. Garcia-Fernandez, R. Dominguez, D. Oberthuer, T.Pons, Y.Gonzalez-Gonzalez, M. A. Chavez, C. Betzel, L. Redecke: Crystal structure of recombinant Kunitz type serine protease inhibitor-1 from the caribbean sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin (2011).

2010

  • Otero-González AJ, Simas Magalhães B, Garcia-Villarino M, López-Abarrategui C, Amaro Sousa D, Campos Dias S, Luiz Franco O. (2010) Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control. FASEB Journal 2010; 0: fj.09-143388v2 (aotero[at]infomed.sld.cu)
  • Otero-González AJ, Simas Magalhães B, Garcia-Villarino M, López-Abarrategui C, Amaro Sousa D, Campos Dias S, Luiz Franco O. (2010) Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control. FASEB Journal, 24, 1320-1334 (FI: 7.12) MEDLINE, WEB of Science)
  • Lazara Romero, Silvana Marcussi, Daniela P. Marchi-Salvador, Floriano P. Silva Jr., André L. Fuly, Rodrigo G. Stábeli, Saulo L. da Silva, Jorge González, Alberto del Monte, Andreimar M. Soares. (2010) Enzymatic and structural characterization of a basic phospholipase A2 from the sea anemone Condylactis gigantea. Biochimie 92:1063-1071.(FI: 3.897) Indexada en la web of Sciences.
  • Jorge González-Bacerio, Jairo Rodríguez Hernández, Alberto del Monte Martínez. (2010). Lipases: enzymes having the potential for developing immobilised biocatalysts by interfacial adsorption. Rev. Colomb. Biotecnol. Vol. XII No. 1,124-140. Indexada en la web of Sciences. (REDALYC, LILACS, DIALNET, CAB, Swets Information Services B.V, INIST, DOAJ, Scielo, EBSCO).
  • García T, Martinez D, Palmero A, Soto C, Tejuca M, Pazos F, Menéndez R, Alvarez C, Garateix A Pharmacological effects of two cytolysins isolated from the sea anemone Stichodactyla helianthus.. J Biosci. 2009 34(6):891-8. Web of Science IF: 1.703 referenciado en PubMed/Medline, Springer.
  • Garcia-Fernandez, R., Redecke, L., Pons, T., Perbandt, M., Talavera, A., Gil, D., Gonzalez, Y., de los Angeles Chavez, M., Betzel, C (2010). Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Carribean sea anemone Stichodactyla helianthus. PDB 3OFW.
  • Garcia-Fernandez, R., Redecke, L., Pons, T., Perbandt, M., Gil, D., Manzur, M., Gonzalez, Y., de los Angeles Chavez, M., Betzel, C (2010). Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean sea anemone Stichodactyla helianthus in complex with bovine pancreatic trypsin. PDB: 3M7Q.
  • Valiente PA, Ley AG, Batista PR, Caffarena ER, Pons T, Pascutti PG. (2010) New parametrization approaches of the LIE method to improve free energy calculations of PlmII-Inhibitors complexes. Journal of Computational Chemistry 31(15): 2723-34. (FI=3.769), PUBMED ID: 20839299.
  • Perera E, Pons T, Hernández D, Moyano FJ, Martínez-Rodríguez G, Mancera JM. (2010) New members of the brachyurins family in lobster include a trypsin-like enzyme with amino acid substitutions in the substrate-binding pocket. FEBS J. 277(17):3489-3501. (FI: FI: 3.042). PUBMED ID: 20649906.
  • Ruiz-Peña M, Oropesa-Núñez R, Pons T, Renaux-Louro S, Pérez-Gramatges A. (2010) Physico-chemical studies of molecular interactions between non-ionic surfactants and bovine serum albumin. Colloids Surf. B: Biointerfaces 75(1):282-9. (FI: 2.600). PUBMED ID: 19782541
  • Otero AJ (2010) Los anticuerpos y su rol como herramientas analíticas en los ensayos inmunoensayos enzimáticos. Rev Cub Med Trop. 62(2): 85-92. (MEDLINE, Scielo)
  • Otero AJ. (2010) Los inmunoensayos enzimáticos para detectar agentes infecciosos o sus productos: Algunos diseños y aplicaciones. Rev Cub Med Trop. 62(3): 167-179 (MEDLINE, Scielo)
  • Gladys Margarita Lugioyo, Orquídea Coto, Carlos Álvarez and Georgina Espinosa (2010). Revista Ciencias Marinas y Costeras Vol 2, pag 65-77 Bacillus species in the oceanic waters adjacent to Cuba: association between their distribution and metabolic activity., (REVMAR, ISSN 1659-455X versión, impresa, ISSN 1659-407X versión digital)
  • Odalys Blanco H., Yuliannis Lugones L, Dayrom F. Gil P, Roberto Faure, Yamile González G. (2009) Human neutrophil elastase and lung surfactant in acute respiratory distress syndrome. Biotecnología Aplicada 2009; 26:1-6.
  • María V. Mederos, Mayra Tejuca, Emir Salas, María de los A. Chávez (2010) Estrategia de cómputo para la resolución de modelos biológicos no lineales. Revista Investigación Operacional Vol 31 No2 pag 281-286
  • Carol Carvajal; Margarita Márquez; Aurora T. Pérez; María de los A. Chávez y Martha Hernández (2010) Caracterización cinética de un preparado semipurificado de bromelina para uso antitumoral Revista Cubana de Plantas Medicinales.15(2).
  • Luzardo MC, Gomes E, Faustino L, Sanchez O, Laborde R, Cruz-Leal Y, Canet L, Alvarez C, Alnso ME, Lanio ME, Russo M (2010). Immunomodulatory properties of liposomes and Sticholysin II in a murine model of asthma. VacciMonitor 19(1): 24. ISSN 1025-028X, EISSN 1025-0298 (SCIELO) (IF= 1.231)
  • Laborde R, Sánchez O, Luzardo MC, Cruz-Leal Y, Canet L, Valle A, Oliver L, Fernández A, Mesa C, Hernández I, Pazos F, Tejuca M, Alvarez C, Alonso ME., Fernández LE., Lanio ME. (2010). Stimulation of cellular immune response by Liposomes encapsulating Sticholysins, pore-forming toxins from the anemone Stichodactyla helianthus. VacciMonitor 19(1): 34. ISSN 1025-028X, EISSN 1025-0298 (SCIELO) (IF= 1.231)
  • Cruz-Leal Y, Machado Y, Sánchez O, Luzardo MC, Canet L, Laborde R, Requena A, Oliver L, Castillo A, de la Luz KR, Alonso ME, Álvarez C, Pérez R, Lanio ME. (2010) B-1 Cells modulate the antibody response induced by an antigen encapsulated in Phosphatidylcholine:Cholesterol liposomes VacciMonitor Vol. 19 Supplement 1: 34. ISSN 1025-028X, EISSN 1025-0298 (SCIELO) (IF= 1.231)
  • Borrero R, García MA, Canet L, Zayas C, Reyes F, Prieto J, Infante JF, Lanio ME, Sarmiento ME, Mohd N and Acosta A. (2010) Evaluation of the humoral immune response and Cross reactivity against mycobacterium tuberculosis of Liposomes containing glycolipids of Mycobacterium smegmatis. VacciMonitor Vol. 19 Supplement 1: 24. ISSN 1025-028X, EISSN 1025-0298 (SCIELO) (IF= 1.231)
  • Alberto del Monte Martínez, Bessy Cutiño-Avila, Dayrom Francisco Gil Pradas, Leonardo Mokarzel Falcón, Jorge González Bacerio, Mario Pupo Meriño, María A. Chávez Planes, Tirso Pons Hernández, Joaquín Díaz Brito (2010). Estrategia de Diseño Racional en la Síntesis de Derivados Inmovilizados. Su implementación mediante el programa RDID1.0. Memorias UCIENCIA 2010. VI Taller de Bioinformática. ISBN 97S-959-2S6-011-7.
  • del Monte-Martínez Alberto, Cutiño-Avila Bessy, Gil Dayrom F., Mokarzel Leonardo, González-Bacerio Jorge, Pupo Mario, Chavez María A., Pons Tirso and Díaz Joaquín. (2010). Advance on the Rational Design of Immobilized Derivatives. RDID Strategy. Memorias IV Simposium Internacional de Química. ISBN 978-959-250-566-7.
  • Cutiño-Avila Bessy, Gil Dayrom F., González-Bacerio Jorge, Mokarzel-Falcón Leonardo, Chavez María A., Díaz Joaquín and del Monte-Martínez Alberto. Algorithm development for protein ionizable group's reactivity on covalent immobilization. Memorias IV Simposium Internacional de Química. ISBN 978-959-250-566-7.

Volver al inicio

2009

  • Alonso-del-Rivero, M., Trejo, SA., Rodríguez-de-la-Vega, M., González, Y., Bronsoms S., Canals, F., Delfín, J., Díaz, J., Avilés F.X., Chávez M.A (2009) A novel metallocarboxypeptidase like enzyme isolated from the marine annelid Sabellastarte magnifica- A step into the invertebrate world of proteases. FEBS Journal 276, 4875-4890 maday[at]fbio.uh.cu.
  • Álvarez C, Mancheño JM, Martínez D, Tejuca M, Pazos F, Lanio ME (2009). Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: Their interaction with membranes. Toxicon 54, 1135-47 calvarez[at]fbio.uh.cu.
  • Ramírez AR, Guerra Y, Otero A, García B, Berry C, Mendiola J, Hernández-Zanui A, Chávez MA. (2009) Generation of an affinity matrix useful in the purification of natural inhibitors of plasmepsin II, an antimalarial-drug target. Biotechnol Appl Biochem. 52: 149-57. mchavez[at]infomed.sld.cu
  • Celedón G, González G, Lissi E, Cerda T, Martínez D, Soto C, Pupo M, Pazos F, Lanio ME, Álvarez C (2009). Effect of calcium on the hemolytic activity of Stichodactyla helianthus toxin sticholysin II on human erythrocytes. Toxicon 54, 845-50 calvarez[at]fbio.uh.cu.
  • Tejuca M, Anderluh G and Dallaserra M. (2009). Sea anemone cytolysins as toxic components of immunotoxins. Toxicon 54:1206-14 tejuca[at]fbio.uh.cu
  • Sánchez E, Vargas MA, Singru PS, Pascual I, Romero F, Fekete C, Charli JL, Lechan RM. (2009) Tanycyte pyroglutamyl peptidase II contributes to regulation of the hypothalamic-pituitary-thyroid axis through glial-axonal associations in the median eminence. Endocrinology 150: 2283-91 isel[at]fbio.uh.cu
  • Ruiz-Peña M, Oropesa-Núñez R, Pons T, Renaux-Louro S, Pérez-Gramatges A. (2009) Physico-chemical studies of molecular interactions between non-ionic surfactants and bovine serum albumin. Colloids Surf. B: Biointerfaces. (doi: 10.1016/j.colsurfb.2009.08.046, PMID: 19782541. pons[at]fbio.uh.cu
  • A del Monte, J. González, L Romero del Sol, C Aragón, F Vega, H Nolasco, J Díaz. (2009) Extraction systems for isolating esterases having interfacial adsorption. Rev. Colomb. Biotecnol. 11, 7-16 (ISSN 0123-3475) adelmonte[at]fbio.uh.cu.
  • Ramírez, A.R., Guerra, Y., Otero, A., García, B. Berry, C., Mendiola, J., Hernández-Zanui, A., Chávez, M.A. (2009) Generation of an affinity matrix useful in the purification of natural inhibitors of plasmepsin II, an antimalarial-drug target. Biotechnology and Applied Biochemistry 52: 32-36 mchavez[at]infomed.sld.cu

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2008

  • Valiente PA, Batista PR, Pupo A, Pons T, Valencia A, Pascutti PG. (2008) Predicting functional residues in Plasmodium falciparum plasmepsins by combining sequence and structural analysis with molecular dynamics simulations. Proteins 73, 440-57 valiente[at]fbio.uh.cu.
  • Cruz R, Vargas MA, Uribe RM, Pascual I, Lazcano I, Yiotakis A, Matziari M, Joseph-Bravo P, Charli JL (2008) Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release. Peptides 29, 1953-1964 isel[at]fbio.uh.cu.
  • Cilli, E.M., Pigossi, F.T., Crusca, E. Jr., Ros, U., Martínez, D., Lanio, M.E., Álvarez, C., Schreier, S. (2007) Correlations between differences in amino terminal sequences and different hemolytic activity of sticholysins. Toxicon 50, 1201-1204 calvarez[at]fbio.uh.cu.
  • Celedón G, González G, Barrientos D, Pino J, Venegas F, Lissi EA, Soto C, Martínez D, Álvarez C, Lanio M. E. (2008) Stycholysin II, a cytolysin from the sea anemone Stichodactyla helianthus promotes higher hemolysis in aged red blood cells. Toxicon 51, 1383-90. mlanio[at]fbio.uh.cu.
  • M.E. Lanio, M.C. Luzardo, C. Álvarez, B. Zadi, Y. Martínez, L. Calderón, M.E. Alonso, D.Q.M. Craig, A. Disalvo, G. Gregoriadis. Humoral immune response against Epidermal Growth Factor encapsulated in Dehydration Rehydration Vesicles of different phospholipid composition. J Liposomes Research. 18: 1 - 19 mlanio[at]fbio.uh.cu.

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2007

  • Martínez, D., Otero, A., Álvarez, C., Pazos, F., Tejuca, M., Lanio, M.E., Gutiérrez-Aguirre, I., Barlic, A., Iloro, I., Rodríguez, J.L., González-Mañas, J.M., Lissi, E. (2007). Effect of sphingomyelin and cholesterol in the interaction of St II lipidic interfaces. Toxicon 49, 68-81 calvarez[at]fbio.uh.cu
  • Lanio, M. E., Álvarez, C., Ochoa, C., Ros, U., Pazos, F., Martínez, D., Tejuca, M., Eugenio, L.M., Casallanovo, F., Dyszy, F.H., Schreier, S., Lissi, E. (2007). Sticholysins I and II interaction with cationic micelles promotes toxins' conformational changes and enhanced hemolytic activity. Toxicon 50, 731-739 mlanio[at]fbio.uh.cu
  • Pascual, I., Gómez, H., López Chappe, M.A., Saroyán, A., González, Y., Cisneros, M., Charli, J.L. and Chávez, MA. (2007) Screening of inhibitors of dipeptidyl peptidase IV activity in aqueous extracts from marine organisms. Enzyme and Microbial Technology. 40, 414-419. isel[at]fbio.uh.cu
  • González, Y., Pons, T., Gil, J., Besada, V., Alonso del Rivero, M., Tanaka, A.S.;, Araujo, M.S. and Chávez, M.A (2007). Characterization and comparative 3D modelling of CmPI-II, a novel "nonclassical" Kazal-type inhibitor from the marine snail Cenchritis muricatus (Mollusca). Biol. Chem. 388, 1183-1194 yamile[at]fbio.uh.cu
  • González, Y., Tanaka, A.S., Hirata, I.Y., del Rivero, M.A., Oliva, M. L. V., Araujo, M. S. and Chávez, M. A. (2007). Purification and preliminary characterization of human neutrophil elastase inhibitors isolated from the marine snail Cenchritis muricatus (Mollusca). Comp. Biochem. Physiol. A Mol Integr Physiol. 146, 506-13 yamile[at]fbio.uh.cu.
  • Silva-López RE, Morgado-Díaz JA, Chávez MA, Giovanni-De-Simone S. (2007). Effects of serine protease inhibitors on viability and morphology of Leishmania (Leishmania) amazonensis promastigotes. Parasitol Res. 101, 1627-1635. mchavez[at]infomed.sld.cu
  • Otero AJ., S, J., H. Hernandez, M. Sánchez, D. Muirragui, M. Villamar, D. Moreta, M. I. Jiménez, L. Pérez, R. H. Maribona (2007). Monoclonal Antibody-based TAS-ELISA for Quantitative Detection of Mycosphaerella fijiensis Antigens. J Phytopathol 155: 713-719 (e-mail: aotero[at]infomed.sld.cu
  • Nolasco, H.; del Monte Martínez, A.; Hinojosa, P.; Civera-Cerecedo, R.; Vega-Villasante, F. (2006). Digestibilidad in vitro de lípidos alimentarios para el camarón. Avances en Nutrición Acuícola 7, 377-395 adelmonte[at]fbio.uh.cu.
  • Pons T, Montero LA, Febles JP. (2007) Computational biology in Cuba: an opportunity to promote science in a developing country. PLoS Comput Biol. 3, 2047-2051 pons[at]fbio.uh.cu.
  • Mansur, M, Martínez, L, Pérez, M, Alonso-del-Rivero, M, Márquez, I, Proenza, Y, Varas, L, and Avilés, FX. (2007) Expression, purification and characterization of porcine pancreatic Carboxypeptidase B from Pichia pastoris for the conversion of recombinant human insulin. Enzyme and Microbial Technology. 40: 476-480 maday[at]fbio.uh.cu

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2006

  • Pazos F, Valle A, Martínez D, Ramírez A, Calderon L, Pupo A, Tejuca M, Morera V, Campos J, Fando R, Dyszy F, Schreier S, Horjales E, Álvarez C, Lanio ME, Lissi E. (2006) Structural and functional characterization of a recombinant sticholysin I (rStI) from the sea anemone Stichodactyla helianthus. Toxicon 48: 1083-1094 fpazos[at]fbio.uh.cu
  • Calderon L, Facenda E, Machado L, Uyema K, Rodriguez D, Gomez E, Martínez Y, González B, Bourg V, Álvarez C, Otero A, Russo M, Labrada A, Lanio ME. (2006) Modulation of the specific allergic response by mite allergens encapsulated into liposomes. Vaccine. 24: S38-S39 mlanio[at]fbio.uh.cu
  • Charli, JL, Pascual, I, Cruz, R, and Vargas, MA. (2006) Post-secretory inactivation of peptides in the hypothalamic-adenohypophyseal axis: Focus on pyroglutamyl peptidase II, the thyrotropin releasing hormone inactivating ectoenzyme. In: Molecular Endocrinology. P. Joseph-Bravo (Ed.), Research Signpost, Transworld Research Network, Kerala, India. pp: 39-64. ISBN 81-308-0100-0 isel[at]fbio.uh.cu
  • Mendiola J, Hernández H, Sariego I, Rojas L, Otero A, Ramírez A, Chávez M de L, Payrol JA, Hernández A. (2006) Antimalarial activity from three ascidians: an exploration of different marine invertebrate phyla. Trans R Soc Trop Med Hyg. 100, 909-916 mchavez[at]infomed.sld.cu
  • Casallanovo F, de Oliveira FJ, de Souza FC, Ros U, Martínez Y, Penton D, Tejuca M, Martínez D, Pazos F, Pertinhez TA, Spisni A, Cilli EM, Lanio ME, Álvarez C, Schreier S. (2006) Model peptides mimic the structure and function of the N-terminus of the pore-forming toxin sticholysin II. Biopolymers 84, 169-80. mlanio[at]fbio.uh.cu
  • Basulto A, Pérez VM, Noa Y, Varela C, Otero AJ, Pico MC. (2006) Immunohistochemical targeting of sea anemone cytolysins on tentacles, mesenteric filaments, and isolated nematocysts of Stichodactyla helianthus. Journal of Experimental Zoology 305, 253-258 mcpico[at]fbio.uh.cu
  • Pons T, González B, Ceciliani F, Galizzi A. (2006). FlgM anti-sigma factors: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships. J. Mol. Model. 12: 973-983 pons[at]fbio.uh.cu
  • Bello, D, Ortega, G, Otero, MA, Saura, G, y Martínez, J. (2006) Poli-hidroxibutiratos. Generalidades, aislamiento y cuantificación. Revista de Plásticos Modernos 91, 81-84 (ISSN 0034-8708) aotero[at]infomed.sld.cu
  • García-Santana MA, Duconge J, Sarmiento ME, Lanio-Ruíz ME, Becquer MA, Izquierdo L, Acosta-Domínguez A. (2006). Biodistribution of liposome-entrapped human gamma-globulin. Biopharm Drug Dispos 27, 275-83. mlanio[at]fbio.uh.cu

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2005

  • G. Celedon, F. Venegas, A.M. Campos, M.E. Lanio, D. Martínez, C. Soto, C. Álvarez, E. Lissi (2005) Role of endogenous channels in red blood cells response to their exposure to the pore forming toxin Sticholysin II. Toxicon 46, 297-307. calvarez[at]fbio.uh.cu
  • Cytotoxic activity of a tumor protease-activated pore forming toxin. Potrich, C., Tomazzolli, R., Dalla Serra, M., Anderluh, G., Malovrh, P., Macek, P., Menestrina, G. & Tejuca, M. (2005). Bioconjugate Chem. 16, 369-376 tejuca[at]fbio.uh.cu

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